Cagrilintide reconstitution calculator

A worked example

Take a 10 mg vial of Cagrilintide and the catalogue's typical dose of 2.4 mg. Add 1 ml of bacteriostatic water and the vial holds 10.0 mg/ml, so one dose is 24 units on a U-100 insulin syringe.

At once a week over 8 weeks that is 8 doses and 19.2 mg in total — 2 vials of 10 mg. One vial covers about 28 days at that rate. Storage on record — Lyophilized: -20°C frozen; Reconstituted: 2-8°C refrigerated, use within 30 days

What the catalogue records

Typical dose

2.4mg weekly (after escalation)

Frequency

Once weekly, same day each week

Cycle duration

Continuous long-term therapy

Half-life

~7 days (159-195 hours)

Storage

Lyophilized: -20°C frozen; Reconstituted: 2-8°C refrigerated, use within 30 days

Mixing a Cagrilintide vial

What you need

• Bacteriostatic water (standard BAC water acceptable for <30 days)
• Optional: 0.6% acetic acid to adjust pH to ~4.0
• Insulin syringes
• Alcohol swabs

Steps

1. CRITICAL: Requires acidic pH (3.5-4.5) to prevent fibril formation
2. Reconstitute slowly down vial side; swirl gently (do not shake)
3. Verify pH 3.5-4.5 after reconstitution
4. Solution must be clear—discard if cloudy or particulate
5. Store refrigerated (2-8°C); inspect before each injection
6. Allow 15-30 minutes to reach room temperature before injection
7. Rotate injection sites weekly

Where this goes next

• Cagrilintide — mechanism, dosing and safety — what it is, what the evidence says, and what it interacts with.
• Build a cycle around it — the cycle builder runs this same arithmetic across every compound you add and totals the vials.
• The general reconstitution calculator — the same tool with nothing prefilled.