LL-37 reconstitution calculator

A worked example

Take a 10 mg vial of LL-37 and the catalogue's typical dose of 500 mcg. Add 2 ml of bacteriostatic water and the vial holds 5.00 mg/ml, so one dose is 10 units on a U-100 insulin syringe.

At once daily over 8 weeks that is 56 doses and 28 mg in total — 3 vials of 10 mg. One vial covers about 20 days at that rate. Storage on record — Lyophilized: 2-8°C. Reconstituted: 2-8°C, maintain sterility

What the catalogue records

Typical dose

0.5-1.6 mg/mL topical gel or 100-150 mcg injectable

Frequency

Topical: Daily to twice weekly on wounds. Injectable: Once daily subcutaneous

Cycle duration

2-8 weeks depending on wound healing progress

Half-life

Short (rapid proteolytic degradation)

Storage

Lyophilized: 2-8°C. Reconstituted: 2-8°C, maintain sterility

Mixing a LL-37 vial

Steps

1. Clean and debride wound area
2. Apply thin layer directly to wound surface
3. Cover with sterile dressing if needed
4. Change per clinical protocol (daily to twice weekly)
5. Monitor healing progress and adjust frequency
6. Document wound measurements and progression

Where this goes next

• LL-37 — mechanism, dosing and safety — what it is, what the evidence says, and what it interacts with.
• Build a cycle around it — the cycle builder runs this same arithmetic across every compound you add and totals the vials.
• The general reconstitution calculator — the same tool with nothing prefilled.