Degenerative cartilage wear in the knee — where repair and anti-inflammatory compounds draw interest.
Knee osteoarthritis is progressive cartilage loss with inflammation and pain. Peptide interest centres on supporting joint tissue and damping inflammation, though cartilage is famously hard to regenerate.
BPC-157 (for joint tissue) and anti-inflammatory peptides like KPV are the usual discussion points, with GHK-Cu sometimes added for connective-tissue support. The evidence base for reversing OA is weak across the board; weight management, strengthening, and clinical care remain primary.
Ranked by editorial relevance — a measure of how central each compound is to the conversation, not a claim of effectiveness.