A comprehensive growth-hormone-axis stack: CJC-1295 + ipamorelin pulse pairing with oral MK-677 for round-the-clock support.
The most complete GH-axis approach short of exogenous HGH: the CJC-1295 + ipamorelin injectable pairing provides clean, pulsatile GH release, while MK-677 (oral ghrelin mimetic) sustains GH/IGF-1 around the clock.
This is for someone deliberately maximising the GH axis for recovery, body composition, and GH-deficiency context — with the trade-offs spelled out: MK-677's appetite, water retention, and insulin-sensitivity effects stack on top of the injectables. Not a beginner stack.
| Compound | Role | Dose | Frequency |
|---|---|---|---|
| CJC-1295 (without DAC) GHRH analogue; pulse amplitude. | Primary | 100-300mcg per injection | 2-3 times daily (morning, post-workout optional, bedtime) |
| Ipamorelin Selective GHRP; triggers the pulse. | Primary | 200-300 mcg per injection | 1-3 times daily depending on goals (1x for longevity, 2-3x for performance) |
| MK-677 Oral ghrelin mimetic; round-the-clock GH/IGF-1. | Support | Start 12.5mg daily, increase to 25mg based on tolerance | Once daily, preferably at bedtime on empty stomach |