A mitochondrial-energy stack pairing injectable NAD+ with the mitochondrial peptide MOTS-c.
This stack targets cellular energy directly: NAD+ (injectable or via oral precursors) for the central redox cofactor, plus MOTS-c, a mitochondrial-derived peptide with exercise-mimetic and metabolic effects.
It overlaps with the Longevity Foundations stack but leans toward energy and exercise capacity rather than the pineal/telomere angle. Evidence is mechanistic and early; treat it as an experiment, not a guarantee.
| Compound | Role | Dose | Frequency |
|---|---|---|---|
| NAD+ Central redox cofactor; route-dependent dosing. | Primary | IV: 250-1000mg; IM/SubQ: 100-500mg; Intranasal: 25-50mg; Oral precursors: 100-500mg NMN/NR | IV: 1-2x weekly; IM/SubQ: 2-3x weekly; Intranasal: 1-2x daily; Oral: daily |
| MOTS-c Mitochondrial peptide; exercise-mimetic. | Support | Start 5mg daily, increase to 10-15mg based on goals | Daily for metabolic support, or 3x weekly for anti-aging |