Goals · Systems & Longevity
Insulin sensitivity, glucose regulation, and energy metabolism.
Compounds linked to this goal in the catalogue, ordered by role — primary, then support, then optional. Click any card for the full mechanism, dosing, and evidence.
NNMT Inhibitor | Longevity & Metabolic Enhancement
Half-life: 4-7 hours (3.8h IV, 6.9h oral)
Prohibitin-Targeting Peptidomimetic | Experimental Anti-Obesity
Half-life: Not established
5-Aminoimidazole-4-carboxamide Ribonucleotide | AMPK Activator
Half-life: ~2-3 hours
Mitochondrial Uncoupler | Metabolic Enhancer
Half-life: ~1.7 hours
Long-Acting Amylin Receptor Agonist | Weight Loss & Diabetes
Half-life: ~7 days (159-195 hours)
GHRH/GHRP Combination | Growth Hormone Optimization
IGF-1 Bioavailability Regulator & Neuroprotective Peptide
Half-life: Extended stability (more stable than linear GPE precursor)
Examorelin | Synthetic Growth Hormone Secretagogue
Half-life: 1-2 hours
Modified Growth Factor Analog | Muscle Growth
Half-life: 20-30 hours
KISS1 Gene Product | Reproductive Neuropeptide
Half-life: ~4 minutes (KP-10), ~28-32 minutes (KP-54)
Amino Acid Derivative | Fatty Acid Transporter
Half-life: ~2-3 hours (injectable)
Synthetic Melanocortin Peptide | Tanning & Sexual Function
Half-life: ~2 hours
Mitochondrial-Derived Peptide | Metabolic Regulator
Half-life: ~30 minutes
Essential Cellular Coenzyme & Anti-Aging Therapy
Half-life: 1-4 hours (intracellular)
KEDW Tetrapeptide | Pancreas Bioregulator
Half-life: Not established
GLP-1 Receptor Agonist | Weight Loss & Diabetes
Half-life: ~7 days (168 hours)
Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator
Half-life: Under investigation (no human PK data)
Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Half-life: Approximately 6 days (109-115 hours)
Tesamorelin + Ipamorelin GH Secretagogue Blend
GHRH Analog | Visceral Fat Reduction
Half-life: 26-38 minutes
Vasoactive Intestinal Peptide | Neuropeptide
Half-life: 1-2 minutes
No SARMs tagged for this goal yet.
Plant Alkaloid | Natural Glucose & Lipid Management
Half-life: ~4 hours
Biguanide | AMPK Activator & Longevity Research
Half-life: ~5 hours
NAD+ Precursor | Cellular Energy & Longevity
Half-life: ~2-3 hours (oral)
Angiotensin II Receptor Blocker | Cardiac Protection On Cycle
Half-life: ~24 hours
Fast-Digesting Dairy Protein | Complete Amino Acid Profile
Half-life: Plasma amino-acid peak at ~60-90 minutes post-ingestion; aminoacidemia returns to baseline within 3-4 hours