Goals · Systems & Longevity
Cellular senescence, telomere health, mitochondrial function. The systemic healthspan play.
Compounds linked to this goal in the catalogue, ordered by role — primary, then support, then optional. Click any card for the full mechanism, dosing, and evidence.
NNMT Inhibitor | Longevity & Metabolic Enhancement
Half-life: 4-7 hours (3.8h IV, 6.9h oral)
AEDL Tetrapeptide | Bronchial Bioregulator
Half-life: Minutes (short peptide); effects persist via epigenetic changes
AEDR | Cardiovascular Bioregulator Peptide
Half-life: Minutes (short peptide); effects persist via epigenetic changes
EDG Tripeptide | Bronchial/Lung Bioregulator
Half-life: Minutes (short peptide); effects persist via epigenetic changes
Short-Acting Growth Hormone Releasing Hormone Analog
Half-life: 30 minutes - 2 hours
Long-Acting Growth Hormone Releasing Hormone Analog | Extended Release
Half-life: 6-8 days
GHRH/GHRP Combination | Growth Hormone Optimization
AEDP | Brain Cortex Bioregulator Peptide
Half-life: Minutes (short peptide); effects persist via epigenetic changes
EDP Tripeptide | Thymus Immune Bioregulator
Half-life: Minutes (short peptide); effects persist via epigenetic changes
Synthetic Pineal Tetrapeptide | Telomerase Activator
Half-life: Not established (short peptide)
Senolytic Peptide | p53-FOXO4 Disruptor
Half-life: Not established
Human Growth Hormone | Somatropin
Half-life: 3-4 hours (SC), 20-30 minutes (IV)
Mitochondria-Derived Peptide | HN
Half-life: ~30 minutes (mice), >4 hours (rats)
KEDA Tetrapeptide | Liver Bioregulator
Half-life: Not established
Mitochondrial-Derived Peptide | Metabolic Regulator
Half-life: ~30 minutes
Essential Cellular Coenzyme & Anti-Aging Therapy
Half-life: 1-4 hours (intracellular)
EDL Tripeptide | Liver & GI Bioregulator
Half-life: Not established
KEDW Tetrapeptide | Pancreas Bioregulator
Half-life: Not established
Synthetic Tripeptide | Neuroprotection & Cognitive Enhancement
Half-life: Not established
Anti-Cancer Peptide | p53-HDM-2 Disruptor
Half-life: Less than 24 hours (requires daily dosing in studies)
KEDP Tetrapeptide | Prostate Bioregulator
Half-life: Not established
Melanocortin Receptor Agonist | Sexual Dysfunction Treatment
Half-life: ~2.7 hours
GHRH Analog | Growth Hormone Releasing Hormone
Half-life: 10-12 minutes
Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator
Half-life: Under investigation (no human PK data)
Mitochondrial-Targeted Peptide | Cardiolipin Protector
Half-life: ~2 hours
Thymic Peptide Bioregulator | Immune Modulator
Half-life: Not established (complex mixture); effects persist for weeks
EW Dipeptide | Thymus Immune Bioregulator
Half-life: Not established
Synthetic Thymic Hormone | Immune System Modulator
Half-life: ~2 hours
ED Dipeptide | Bladder & Urinary Tract Bioregulator
Half-life: Not established
KED | Vascular Bioregulator Peptide
Half-life: Not established
KE Dipeptide | Thymus Immune Bioregulator
Half-life: Not established
No SARMs tagged for this goal yet.
Plant Alkaloid | Natural Glucose & Lipid Management
Half-life: ~4 hours
Biguanide | AMPK Activator & Longevity Research
Half-life: ~5 hours
Mitochondrial Electron Carrier | Cognitive & Neuroprotection
Half-life: ~5-6 hours
Mucolytic | Glutathione Precursor | FDA-Approved Drug
Half-life: ~6 hours (oral); plasma cysteine elevation persists ~12 hours
NAD+ Precursor | Cellular Energy & Longevity
Half-life: ~2-3 hours (oral)
HMG-CoA Reductase Inhibitor | Low-Interaction Statin
Half-life: ~12 hours
mTOR Inhibitor | Longevity & Immunosuppression
Half-life: ~62 hours
HMG-CoA Reductase Inhibitor | Statin for Lipid Management
Half-life: ~19 hours
Conditionally-Essential Amino Sulfonic Acid | Cardio & Mitochondrial Support
Half-life: ~1 hour (plasma) but tissue stores are large and slowly turn over
Fast-Digesting Dairy Protein | Complete Amino Acid Profile
Half-life: Plasma amino-acid peak at ~60-90 minutes post-ingestion; aminoacidemia returns to baseline within 3-4 hours