Normal aging-related slips in memory and processing — where neurotrophic and longevity compounds are studied.
Normal cognitive aging (distinct from dementia) draws interest in neurotrophic peptides (Semax family) and longevity-leaning compounds (NAD+, rapamycin) that target the biology of brain aging.
Evidence in healthy older adults is thinner than in clinical populations. Cardiovascular health, exercise, sleep, and social/cognitive engagement remain the best-evidenced protective factors; these compounds are speculative adjuncts.
Ranked by editorial relevance — a measure of how central each compound is to the conversation, not a claim of effectiveness.
| Compound | Type | Why it's relevant |
|---|---|---|
| NA Semax Amidate | peptide | Neurotrophic; BDNF support. |
| NAD+ | peptide | Cellular-energy support for brain aging. |
| Rapamycin | supplement | mTOR inhibitor; longevity/neuro interest. |