Cartalax
Also known as: AED peptide, T-31, Sigumir, Kartalaks
Bioregulatory Tripeptide | Cartilage & Connective Tissue Support
Overview
Synthetic tripeptide developed by Professor Vladimir Khavinson, supporting cartilage, connective tissue, and cellular regeneration through proliferation markers and apoptosis pathway modulation.
Key benefits
- Joint and connective tissue support
- Potential anti-aging effects on fibroblasts
- Cartilage regeneration support
- Established safety profile in Russian clinical practice
Mechanism of action
Modulates cell proliferation, suppresses apoptosis, affects fibroblast activity, reduces senescence markers, and influences extracellular matrix preservation.
Molecular data
- Type
- Tripeptide
- Half-life
- Minutes (short peptide); effects persist via epigenetic changes
Sequence
Ala-Glu-Asp (AED)
Indications
What the research community uses this compound for, with self-reported effectiveness.
Joint Health
Osteoarthritis
EffectiveClinical efficacy shown in osteochondrosis, osteoarthritis, and osteoporosis treatment.
Degenerative Joint Disease Prevention
ModerateSupports cartilage maintenance and joint function.
Post-Fracture Recovery
ModerateSupports bone and connective tissue healing.
Skin Health
Fibroblast Activation
EffectiveIncreased Ki-67 expression with suppressed apoptosis in young and aged cells.
Collagen Production
EffectiveEnhances collagen synthesis in connective tissue.
Cellular Senescence Reduction
ModerateInhibited MMP-9 synthesis; maintained extracellular matrix integrity.
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Oral
Capsule form; do not chew, swallow whole with water during meals.
| Protocol | Dose | Frequency | Route / duration |
|---|---|---|---|
| Joint Support | 100-200mcg (1-2 capsules) | 1-2x daily with meals | Oral |
Injectable
Daily subcutaneous injection for enhanced bioavailability.
| Protocol | Dose | Frequency | Route / duration |
|---|---|---|---|
| Tissue Regeneration | 700-1400mcg (10-20mcg/kg) | Daily | SubQ |
Preparation
You will need
- Cartalax lyophilized powder
- Bacteriostatic water
- Insulin syringes
- Alcohol swabs
Steps
- Use bacteriostatic water for reconstitution
- Gentle mixing required
- Store refrigerated after reconstitution
Work out the water volume and syringe units in the reconstitution calculator →
Topical
Solution applied to face, neck, hands, or superficial joint areas.
| Protocol | Dose | Frequency | Route / duration |
|---|---|---|---|
| Skin Rejuvenation | 0.5-1ml solution | 2x daily | Topical |
Interactions
Pairwise interactions with other compounds you might be cycling — the same data behind the cycle builder's safety check.
Growth Factors (IGF-1, GH)
MonitorBoth affect tissue growth; monitor for excessive proliferation.
Other Khavinson Peptides
SynergisticComplementary bioregulatory effects across organ systems.
Collagen Supplements
SynergisticMay enhance synthesis while supplements provide raw materials.
BPC-157
CompatibleDifferent mechanisms; no direct interaction.
TB-500
CompatibleDistinct action pathways; may complement effects.
Glucosamine/Chondroitin
SynergisticComplementary joint support mechanisms.
Timeline
Typical week-by-week effects reported in clinical and observational data.
- Week 1-2
Establishing baseline; minimal noticeable changes
- Week 3-4
Gradual improvement in joint comfort
- Month 2
Noticeable mobility improvements
- Month 3
Maximum therapeutic effect achieved
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- No reported side effects in Russian clinical use when taken properly
- Well-tolerated in elderly patients
Stop signs — stop and seek advice
- Allergic reactions
- Digestive upset (rare with proper administration)
- No improvement after 3 months
- Unexpected symptoms
Contraindications
- Pregnancy and breastfeeding
- Active cancer (theoretical proliferation risk)
Monitoring
- Follow official Russian manufacturer timing guidelines
- Take with meals for oral form
Quality checks
What a legitimate product looks like, what should give pause, and what should make you stop.
Good signs
- Professional Russian packaging with holographic seals
- Exactly 0.1mg (100mcg) AC-4 peptide complex per capsule
- Clear Russian/English instructions specifying 'with meals'
Warning signs
- Proper documentation required for authenticity
- Import verification needed
Stop signs — don't use
- Missing holographic seals or professional packaging
- Unclear dosing instructions
References
Primary literature and clinical-trial data informing this entry.
Fibroblast Proliferation Study
2019
Human skin fibroblasts; 72 hours at 20 nM. Increased Ki-67 expression with suppressed apoptosis in young and aged cells.
Kidney Cell Culture Research
2020
Renal epithelial cells; 7 days. Reduced pro-apoptotic p53 expression in aging kidney cells.
Clinical Spine & Joint Study (Russia)
N/A
Human subjects; 1-3 months with 0.1mg capsules daily. Efficacy in osteochondrosis, osteoarthritis, and osteoporosis treatment.
Matrix Metalloproteinase Research
2020
Fibroblast cultures; 5 days at 20 nM. Inhibited MMP-9 synthesis; maintained extracellular matrix integrity.
Last updated . How this page was sourced is described in the methodology.