PeptidePreclinical
Adalank
Also known as: N-Acetyl Selank Amidate, ADA
N-Acetyl Selank Amidate | Enhanced Tuftsin Analog
Overview
Enhanced derivative of Selank with improved stability, blood-brain barrier penetration, and extended half-life compared to parent compound. Parent compound Selank approved in Russia since early 2000s.
Key benefits
- Potent anxiolytic effects without sedation
- Enhanced cognitive function
- Stress resilience
- Improved mood and emotional stability
- Neuroprotection via BDNF upregulation
- No tolerance, dependency, or withdrawal
Mechanism of action
Modulates GABAergic neurotransmission, upregulates hippocampal BDNF, influences serotonin metabolism, and provides immunomodulatory effects without benzodiazepine-like dependency.
Molecular data
- Type
- Modified heptapeptide
- Half-life
- Not established
Sequence
Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2
Indications
What the research community uses this compound for, with self-reported effectiveness.
Anxiety
Cognitive
Neuroprotection
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 200-300mcg | 1x daily (morning) | — |
| — | 200-500mcg | 1x daily | — |
| — | 200-300mcg | 2x daily (morning, afternoon) | — |
| — | 100-200mcg | 1x daily | — |
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 200-300mcg per dose | 2-3x daily (600-900mcg total) | — |
| — | 150-200mcg per dose | 2x daily | — |
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- Parent compound has high safety profile in Russian clinical research
- Minimal side effects reported
Contraindications
- Experimental peptide with limited direct human research on N-Acetyl form
- Not recommended during pregnancy or breastfeeding
- Consult healthcare provider before use with psychiatric medications
Monitoring
- Use sterile injection technique
- Start with lower doses (100-200mcg) to assess response
- Cycle with 1-2 week breaks to prevent tolerance