PeptidePreclinical
Pinealon
Also known as: EDR, Glu-Asp-Arg, Cerluten
Synthetic Tripeptide | Neuroprotection & Cognitive Enhancement
Overview
Developed in Russia, Pinealon demonstrates unique DNA-interaction for neuroprotection and cognitive enhancement. Benefits traumatic brain injury recovery and age-related cognitive decline with excellent safety profile.
Key benefits
- Direct DNA interaction
- Neuroprotection
- Cognitive enhancement
- Excellent safety profile
- 40+ years of clinical use in Russia
Mechanism of action
Penetrates nuclear membranes to directly interact with DNA, modulates gene expression via histone H1.3 binding and MAPK/ERK pathway activation.
Molecular data
- Type
- Tripeptide
- Half-life
- Not established
Sequence
Glu-Asp-Arg (EDR)
Indications
What the research community uses this compound for, with self-reported effectiveness.
Neuroprotection
Cognitive
Anti-Aging
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 5mg daily | Once daily | — |
| — | 100-300mcg | Daily or every other day | — |
| — | 5mg | 20 days, 2-3x yearly | — |
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 0.2mg twice daily | Morning and afternoon | — |
| — | 200mcg | Daily | — |
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- Minimal injection site reactions
- Mild gastrointestinal adjustment
- Occasional headache
- Fatigue
Contraindications
- Pregnancy
- Lactation
Monitoring
- Medical supervision recommended
- Rotate injection sites
- Use sterile technique