Vilon
Also known as: KE, Lys-Glu, Thymus Dipeptide, Immunget
KE Dipeptide | Thymus Immune Bioregulator
Overview
Vilon is a Khavinson bioregulator dipeptide (KE) consisting of lysine and glutamic acid, originally isolated from thymus gland extracts. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it acts as a molecular signaling compound that restores normal gene expression and protein synthesis in immune and epithelial cells. Research shows Vilon increases mean lifespan by 20-40% in animal studies and suppresses tumor development.
Key benefits
- Increases mean lifespan 20-40% in animal models
- Suppresses tumor development
- Stimulates thymocyte proliferation
- Activates T-helper cells
- Restores chromatin structure in aged lymphocytes
- Enhances intestinal barrier function
- Improves enzyme activity in aged tissue
- Part of comprehensive longevity protocols
Mechanism of action
Vilon works through epigenetic modulation, restoring chromatin structure and gene expression in immune cells. It stimulates thymocyte proliferation, activates T-helper cells, and increases the proliferative index in thymus tissue (from 26% to 37% in studies). The peptide modulates tyrosine phosphorylation of mitogen-activated cytoplasmic kinases and helps rejuvenate aged immune systems by restoring proper gene expression patterns.
Molecular data
- Type
- Dipeptide bioregulator
- Half-life
- Not established
Sequence
Lys-Glu
Indications
What the research community uses this compound for, with self-reported effectiveness.
Immune Support
Anti-Aging
GI Health
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 10-20 mg | Daily for 10-20 days | — |
| — | 10 mg | 2-3 cycles yearly | — |
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 10 mg | Daily for 10 days | — |
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- Generally well-tolerated
- Minimal side effects reported
Rare side effects
- Allergic reactions (rare)
Contraindications
- Active autoimmune flares (consult physician)
- Known hypersensitivity
- Pregnancy or breastfeeding