Goals · Body & Composition
Lose body fat while preserving lean tissue. Most approaches combine appetite control, lipolysis support, and metabolic optimization.
Compounds linked to this goal in the catalogue, ordered by role — primary, then support, then optional. Roles follow peptide-db's per-use effectiveness rating (most effective → primary, effective → support, moderate or thinner → optional); a compound that reaches the goal through a curated stack or a condition page says so. Click any card for the full mechanism, dosing, and evidence.
Modified hGH Fragment | Fat Loss Peptide
Half-life: 3-4 minutes
Long-Acting Amylin Receptor Agonist | Weight Loss & Diabetes
Half-life: ~7 days (159-195 hours)
Growth Hormone Fragment | Fat Loss Peptide
Half-life: 15-20 minutes
Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Half-life: 6-8 days
Mitochondrial-Derived Peptide | Metabolic Regulator
Half-life: ~30 minutes
Oral Small-Molecule GLP-1 Receptor Agonist | Weight Loss & Diabetes
Half-life: 25-68 hours
Triple GLP-1/GIP/Glucagon Agonist | Weight Loss & Diabetes
Half-life: ~6 days
GLP-1 Receptor Agonist | Weight Loss & Diabetes
Half-life: ~7 days (168 hours)
Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Half-life: Approximately 6 days (109-115 hours)
GHRH Analog | Visceral Fat Reduction
Half-life: 26-38 minutes
Dual GIP/GLP-1 Receptor Agonist | Weight Loss & Diabetes
Half-life: ~5 days (120 hours)
Short-Acting Growth Hormone Releasing Hormone Analog
Half-life: 30 minutes - 2 hours
Support — Curated stack: GH-Fragment Recomp
NNMT Inhibitor | Longevity & Metabolic Enhancement
Half-life: 4-7 hours (3.8h IV, 6.9h oral)
Optional — Metabolic Rate Enhancement · moderate
Prohibitin-Targeting Peptidomimetic | Experimental Anti-Obesity
Half-life: Not established
Optional — Development halted after Phase 1 on kidney safety signals
Body Protection Compound-157 | Pentadecapeptide
Half-life: <30 minutes
Optional — Curated stack: Lean Preservation (Ostarine)
L-Glutathione | Master Antioxidant Tripeptide
Half-life: ~10-14 minutes (IV)
Optional — Researched for Non-Alcoholic Fatty Liver (NAFLD)
Amino Acid Derivative | Fatty Acid Transporter
Half-life: ~2-3 hours (injectable)
Optional — Curated stack: GLP-1 Fat-Loss Starter
Beta-2 Agonist | Thermogenic Fat Loss
Half-life: ~36 hours
Support — Cutting Phase Fat Loss · effective
Biguanide | AMPK Activator & Longevity Research
Half-life: ~5 hours
Support — Researched for Type 2 Diabetes
Plant Alkaloid | Natural Glucose & Lipid Management
Half-life: ~4 hours
Optional — Researched for Type 2 Diabetes
Mucolytic | Glutathione Precursor | FDA-Approved Drug
Half-life: ~6 hours (oral); plasma cysteine elevation persists ~12 hours
Optional — Researched for Non-Alcoholic Fatty Liver (NAFLD)