IllumiNeuro Protocol
Also known as: IllumiNeuro, Neuro Stack
Four-Peptide Cognitive Enhancement Blend
Overview
IllumiNeuro is a cognitive enhancement peptide blend combining four nootropic peptides: PE-22-28 (neuritogenic), Pinealon (pineal bioregulator), NA-Semax Amidate (neuroprotective/cognitive), and NA-Selank Amidate (anxiolytic/cognitive). The standard formulation contains 48mg total (PE-22-28 10mg + Pinealon 10mg + NA-Semax 20mg + NA-Selank 8mg). This blend targets multiple neurological pathways for comprehensive cognitive support, though no clinical studies exist on this specific four-peptide combination.
Key benefits
- Multi-pathway cognitive enhancement
- Neuroprotective and neuritogenic effects
- Anxiolytic properties from NA-Selank
- BDNF upregulation from NA-Semax
- Circadian/sleep support from Pinealon
- Convenience of single injection
- Extended-action amidate forms included
Mechanism of action
Each peptide contributes distinct neurological mechanisms: PE-22-28 promotes neurite outgrowth and neural connectivity through sphingosine-1-phosphate receptor modulation; Pinealon is a bioregulator that supports pineal gland function and circadian regulation; NA-Semax Amidate provides BDNF upregulation and neuroprotection; NA-Selank Amidate offers anxiolytic effects through GABA modulation and immune-neuroendocrine regulation. Together, they theoretically address cognitive enhancement, neuroprotection, mood support, and neural regeneration.
Molecular data
- Type
- Fixed-ratio peptide combination
Sequence
PE-22-28 + Pinealon + NA-Semax + NA-Selank
Indications
What the research community uses this compound for, with self-reported effectiveness.
Cognitive Enhancement
Mood & Anxiety
Neural Health
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 100-200mcg total blend | Once daily (morning) | — |
| — | 200-400mcg total blend | Once daily | — |
| — | 400-500mcg total blend | Once daily | — |
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 100-300mcg | Once or twice daily | — |
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- Injection site reactions (mild)
- Nasal irritation if used intranasally
- Possible vivid dreams (Pinealon effect)
- Mild headache initially
Rare side effects
- Overstimulation or anxiety (paradoxical)
- Sleep changes
Contraindications
- No clinical trials on four-peptide combination
- Bipolar disorder or psychosis (caution with cognitive enhancers)
- Pregnancy or breastfeeding
- Seizure disorders (theoretical concern)
Monitoring
- Cognitive function and focus
- Mood and anxiety levels
- Sleep quality
- Any unusual neurological symptoms