Ovagen
Also known as: EDL, Glu-Asp-Leu, Liver Tripeptide, GI Bioregulator
EDL Tripeptide | Liver & GI Bioregulator
Overview
Ovagen is a Khavinson bioregulator tripeptide (EDL) with primary effects on the liver and gastrointestinal tract. Developed by Dr. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it reduces long-term liver fibrosis and protects the GI mucosal layer from antibiotics, environmental toxins, and chemotherapy. Like other bioregulators, Ovagen crosses cell and nuclear membranes to directly regulate DNA transcription patterns with tissue-specific effects.
Key benefits
- Reduces long-term liver fibrosis
- Protects GI mucosal layer
- Defense against antibiotic damage
- Protection from environmental toxins
- May protect against chemotherapy GI effects
- Tissue-specific targeting via PEPT transporters
- Direct DNA regulation
- Part of comprehensive anti-aging protocols
Mechanism of action
Ovagen works through epigenetic regulation by crossing cell and nuclear membranes to directly regulate DNA structure and transcription patterns. It is transported into cells via POT family transporters (PEPT1, PEPT2) that specifically handle di- and tripeptides, explaining its precise tissue targeting. The peptide has tissue-specific effects on liver and GI tract, reducing fibrosis and protecting mucosal integrity.
Molecular data
- Type
- Tripeptide bioregulator
- Formula
- C15H25N3O8
- Half-life
- Not established
Sequence
Glu-Asp-Leu
Indications
What the research community uses this compound for, with self-reported effectiveness.
Liver Support
GI Protection
Anti-Aging
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 10-20 mg | Daily for 10-20 days | — |
| — | 10 mg | 2-3 cycles yearly | — |
Delivery method
| Protocol | Dose | Frequency | Duration |
|---|---|---|---|
| — | 10 mg | Daily for 10 days | — |
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- Generally well-tolerated
- Minimal side effects reported
Rare side effects
- Allergic reactions (rare)
Contraindications
- Active liver emergencies (seek medical care)
- Known hypersensitivity
- Pregnancy or breastfeeding