Prostamax
Also known as: KEDP, Lys-Glu-Asp-Pro, Prostate Bioregulator, Prostatic Peptide, Libidon
KEDP Tetrapeptide | Prostate Bioregulator
Overview
Prostamax is a Khavinson bioregulator tetrapeptide (KEDP) with primary repair effects on prostate tissue. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it alters chromatin structure in cells from elderly individuals, promoting deheterochromatinization and potentially reactivating genes repressed during aging. Research in rat models shows reduced prostate inflammation, decreased swelling, and decelerated pathological remodeling associated with prostatitis.
Key benefits
- Reduces prostate inflammation
- Decreases prostatic swelling
- Reduces vascular congestion (hyperemia)
- Decreases immune cell infiltration
- Reduces scarring in prostate tissue
- Promotes chromatin decondensation
- Reactivates age-repressed genes
- Improves lymphocyte function
Mechanism of action
Prostamax works through epigenetic regulation by altering chromatin structure. It increases the frequency of sister chromatid exchanges and Ag-positive nucleolar organizer regions (NORs), while reducing large segments of pericentromeric heterochromatin. These changes promote chromatin decondensation and deheterochromatinization, potentially reactivating genes repressed during aging. The peptide influences heterochromatin arrangements in human lymphocytes and normalizes age-related changes in cellular function.
Molecular data
- Type
- Tetrapeptide bioregulator
- Half-life
- Not established
Sequence
Lys-Glu-Asp-Pro
Indications
What the research community uses this compound for, with self-reported effectiveness.
Prostate Health
Chronic Prostatitis
EffectiveResearch shows reduced inflammation and swelling in prostatitis models.
Prostatic Inflammation
EffectiveMitigates inflammation and immune cell infiltration in prostate tissue.
Prostate Tissue Repair
ModerateDecreases scarring and pathological remodeling in prostate.
Anti-Aging
Chromatin Remodeling
EffectivePromotes deheterochromatinization in elderly cells.
Gene Reactivation
ModeratePotentially reactivates genes repressed during aging process.
Lymphocyte Function
ModerateNormalizes age-related changes in lymphocyte function.
Dosing protocols
Common protocols by delivery method. Adjust the curve below to model accumulation in your own cycle.
Oral
Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles.
| Protocol | Dose | Frequency | Route / duration |
|---|---|---|---|
| Standard protocol | 10-20 mg | Daily for 10-20 days | Oral capsules |
| Maintenance | 10 mg | 2-3 cycles yearly | Oral capsules |
Injectable
Injectable form available for direct administration.
| Protocol | Dose | Frequency | Route / duration |
|---|---|---|---|
| Research protocol | 10 mg | Daily for 10-15 days | IM or SubQ |
Preparation
You will need
- Bacteriostatic water
- Insulin syringes
- Alcohol swabs
- Sterile vial
Steps
- Clean work area thoroughly
- Reconstitute with appropriate volume
- Gently swirl until dissolved
- Store reconstituted solution refrigerated
Work out the water volume and syringe units in the reconstitution calculator →
Interactions
Pairwise interactions with other compounds you might be cycling — the same data behind the cycle builder's safety check.
Testagen
SynergisticComplementary male reproductive bioregulators; different tissue targets.
Epitalon
SynergisticOften combined in comprehensive anti-aging Khavinson protocols.
Vilon
CompatibleDifferent organ targets; can be used in comprehensive bioregulator protocols.
Crystagen
CompatiblePart of Khavinson bioregulator family; targets different tissue.
Timeline
Typical week-by-week effects reported in clinical and observational data.
- During cycle
Chromatin remodeling and gene expression changes begin
- Post-cycle
Effects persist due to epigenetic changes
- Weeks-Months
Prostate function improvements
- Long-term
Cumulative benefits with periodic cycles
Safety
Reported adverse effects, contraindications, and what to monitor on cycle.
Common side effects
- Generally well-tolerated
- Minimal side effects reported
Rare side effects
- Allergic reactions (rare)
Stop signs — stop and seek advice
- Allergic reactions
- Unusual urinary symptoms
Contraindications
- Prostate cancer (consult oncologist)
- Known hypersensitivity
- Pregnancy (not applicable)
Monitoring
- PSA testing recommended for men over 50
- Urological evaluation if symptoms persist
Quality checks
What a legitimate product looks like, what should give pause, and what should make you stop.
Good signs
- White powder or capsules
- Clear solution if reconstituted
- Proper packaging and labeling
Warning signs
- Unknown source or purity
Stop signs — don't use
- Discoloration
- Unusual odor
- Damaged packaging
References
Primary literature and clinical-trial data informing this entry.
Experimental Studying of Drug Efficiency Prostamax in Therapy of Chronic Aseptic Prostatitis
Bulletin of Experimental Biology and Medicine · 2013
Prostamax reduced prostate swelling, inflammation, and scarring in rat prostatitis models.
Effects of Short Peptides on Lymphocyte Chromatin in Senile Subjects
Bulletin of Experimental Biology and Medicine · 2004
KEDP peptide alters chromatin structure, promoting deheterochromatinization in elderly cells.
Deheterochromatinization of Chromatin in Old Age Induced by Oligopeptide Bioregulator (Lys-Glu-Asp-Pro)
Georgian Medical News · 2012
Prostamax promotes chromatin decondensation and reactivates age-repressed genes.
Khavinson Peptide Bioregulators
Advances in Gerontology · 2020
Comprehensive review of bioregulator peptides and their epigenetic mechanisms.
Last updated . How this page was sourced is described in the methodology.