Goals · Systems & Longevity
Lipid profile, endothelial function, blood pressure, and cardioprotection.
Compounds linked to this goal in the catalogue, ordered by role — primary, then support, then optional. Roles follow peptide-db's per-use effectiveness rating (most effective → primary, effective → support, moderate or thinner → optional); a compound that reaches the goal through a curated stack or a condition page says so. Click any card for the full mechanism, dosing, and evidence.
Triple GLP-1/GIP/Glucagon Agonist | Weight Loss & Diabetes
Half-life: ~6 days
Vasoactive Intestinal Peptide | Neuropeptide
Half-life: 1-2 minutes
Relaxin-2 Analog | Anti-Fibrotic & Cardiovascular
Half-life: Not well characterized
Support — Cardiac Fibrosis · effective
AEDR | Cardiovascular Bioregulator Peptide
Half-life: Minutes (short peptide); effects persist via epigenetic changes
Support — Cardiac Tissue Repair · effective
Examorelin | Synthetic Growth Hormone Secretagogue
Half-life: 1-2 hours
Support — Cardioprotection · effective
Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Half-life: 6-8 days
Support — Blood Pressure Reduction · effective
Mitochondrial-Targeted Peptide | Cardiolipin Protector
Half-life: ~2 hours
Support — Cardiac Protection · effective
Dual GIP/GLP-1 Receptor Agonist | Weight Loss & Diabetes
Half-life: ~5 days (120 hours)
Support — MACE Reduction · effective
KED | Vascular Bioregulator Peptide
Half-life: Not established
Support — Vascular Aging · effective
5-Aminoimidazole-4-carboxamide Ribonucleotide | AMPK Activator
Half-life: ~2-3 hours
Optional — Ischemia Protection · moderate
Melanocortin Receptor Agonist | Sexual Dysfunction Treatment
Half-life: ~2.7 hours
Optional — Researched for Erectile Dysfunction
Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator
Half-life: Under investigation (no human PK data)
Optional — Cardiac Function Improvement · moderate
No SARMs tagged for this goal yet.
Cholesterol Absorption Inhibitor | Lipid Management On Cycle
Half-life: ~22 hours
Beta Blocker | Heart Rate & Anxiety Management
Half-life: ~4-5 hours
HMG-CoA Reductase Inhibitor | Statin for Lipid Management
Half-life: ~19 hours
PDE5 Inhibitor | Erectile Function & Pulmonary Hypertension
Half-life: ~3-5 hours
PDE5 Inhibitor | Erectile Function & Blood Flow
Half-life: ~17.5 hours
Angiotensin II Receptor Blocker | Cardiac Protection On Cycle
Half-life: ~24 hours
Metabolic Modulator | Endurance & Cardioprotection
Half-life: ~4-6 hours
Support — Ischemic Heart Disease · effective
HMG-CoA Reductase Inhibitor | Low-Interaction Statin
Half-life: ~12 hours
Support — Primary Hyperlipidemia · effective
Conditionally-Essential Amino Sulfonic Acid | Cardio & Mitochondrial Support
Half-life: ~1 hour (plasma) but tissue stores are large and slowly turn over
Support — Chronic Heart Failure (Adjunct) · effective
Chelated Magnesium | Sleep, Recovery & Cardiovascular Support
Half-life: ~30 hours (whole-body); urinary excretion is the primary regulator
Optional — Blood Pressure · moderate
NAD+ Precursor | Cellular Energy & Longevity
Half-life: ~2-3 hours (oral)
Optional — Vascular Health · moderate