Goals · Systems & Longevity
Lipid profile, endothelial function, blood pressure, and cardioprotection.
Compounds linked to this goal in the catalogue, ordered by role — primary, then support, then optional. Click any card for the full mechanism, dosing, and evidence.
5-Aminoimidazole-4-carboxamide Ribonucleotide | AMPK Activator
Half-life: ~2-3 hours
Relaxin-2 Analog | Anti-Fibrotic & Cardiovascular
Half-life: Not well characterized
AEDR | Cardiovascular Bioregulator Peptide
Half-life: Minutes (short peptide); effects persist via epigenetic changes
Examorelin | Synthetic Growth Hormone Secretagogue
Half-life: 1-2 hours
Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Half-life: 6-8 days
Triple GLP-1/GIP/Glucagon Agonist | Weight Loss & Diabetes
Half-life: ~6 days
Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator
Half-life: Under investigation (no human PK data)
Mitochondrial-Targeted Peptide | Cardiolipin Protector
Half-life: ~2 hours
Thymosin Beta-4 Active Fragment | Healing Peptide
Half-life: Not precisely established; effects persist longer than 24 hours
43-Amino Acid Regenerative Peptide | Tissue Repair & Healing
Half-life: Dose-dependent; relatively short (exact values not established)
Dual GIP/GLP-1 Receptor Agonist | Weight Loss & Diabetes
Half-life: ~5 days (120 hours)
KED | Vascular Bioregulator Peptide
Half-life: Not established
Vasoactive Intestinal Peptide | Neuropeptide
Half-life: 1-2 minutes
No SARMs tagged for this goal yet.
Cholesterol Absorption Inhibitor | Lipid Management On Cycle
Half-life: ~22 hours
Chelated Magnesium | Sleep, Recovery & Cardiovascular Support
Half-life: ~30 hours (whole-body); urinary excretion is the primary regulator
Metabolic Modulator | Endurance & Cardioprotection
Half-life: ~4-6 hours
NAD+ Precursor | Cellular Energy & Longevity
Half-life: ~2-3 hours (oral)
HMG-CoA Reductase Inhibitor | Low-Interaction Statin
Half-life: ~12 hours
Beta Blocker | Heart Rate & Anxiety Management
Half-life: ~4-5 hours
HMG-CoA Reductase Inhibitor | Statin for Lipid Management
Half-life: ~19 hours
PDE5 Inhibitor | Erectile Function & Pulmonary Hypertension
Half-life: ~3-5 hours
PDE5 Inhibitor | Erectile Function & Blood Flow
Half-life: ~17.5 hours
Conditionally-Essential Amino Sulfonic Acid | Cardio & Mitochondrial Support
Half-life: ~1 hour (plasma) but tissue stores are large and slowly turn over
Angiotensin II Receptor Blocker | Cardiac Protection On Cycle
Half-life: ~24 hours